Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences

BACKGROUND: Positive selection pressure acting on protein-coding sequences is usually inferred when the rate of nonsynonymous substitution is greater than the synonymous rate. However, purifying selection acting directly on the nucleotide sequence can lower the synonymous substitution rate. This cou...

Descripción completa

Detalles Bibliográficos
Autores principales: Ngandu, Nobubelo K, Scheffler, Konrad, Moore, Penny, Woodman, Zenda, Martin, Darren, Seoighe, Cathal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666660/
https://www.ncbi.nlm.nih.gov/pubmed/19105834
http://dx.doi.org/10.1186/1743-422X-5-160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666660/
https://www.ncbi.nlm.nih.gov/pubmed/19105834
http://dx.doi.org/10.1186/1743-422X-5-160

Ejemplares similares