Cargando…

A functional type I topoisomerase from Pseudomonas aeruginosa

BACKGROUND: Pseudomonas aeruginosa encodes a putative topoisomerase with sequence similarity to the eukaryotic type IB topoisomerase from Vaccinia virus. Residues in the active site are conserved, notably Tyr292 which would be predicted to form the transient covalent bond to DNA. RESULTS: The gene e...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Teesta, Roper, Benjamin J, Grove, Anne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666729/
https://www.ncbi.nlm.nih.gov/pubmed/19317906
http://dx.doi.org/10.1186/1471-2199-10-23