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Expression of excess receptors and negative feedback control of signal pathways are required for rapid activation and prompt cessation of signal transduction
BACKGROUND: Cellular signal transduction is initiated by the binding of extracellular ligands to membrane receptors. Receptors are often expressed in excess, and cells are activated when a small number of receptors bind ligands. Intracellular signal proteins are activated at a high level soon after...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666736/ https://www.ncbi.nlm.nih.gov/pubmed/19254388 http://dx.doi.org/10.1186/1478-811X-7-3 |