Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone

During development, growth factors and hormones cooperate to establish the unique sizes, shapes and material properties of individual bones. Among these, TGF-β has been shown to developmentally regulate bone mass and bone matrix properties. However, the mechanisms that control postnatal skeletal int...

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Detalles Bibliográficos
Autores principales: Mohammad, Khalid S., Chen, Carol G., Balooch, Guive, Stebbins, Elizabeth, McKenna, C. Ryan, Davis, Holly, Niewolna, Maria, Peng, Xiang Hong, Nguyen, Daniel H. N., Ionova-Martin, Sophi S., Bracey, John W., Hogue, William R., Wong, Darren H., Ritchie, Robert O., Suva, Larry J., Derynck, Rik, Guise, Theresa A., Alliston, Tamara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666804/
https://www.ncbi.nlm.nih.gov/pubmed/19357790
http://dx.doi.org/10.1371/journal.pone.0005275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666804/
https://www.ncbi.nlm.nih.gov/pubmed/19357790
http://dx.doi.org/10.1371/journal.pone.0005275

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