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Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone
During development, growth factors and hormones cooperate to establish the unique sizes, shapes and material properties of individual bones. Among these, TGF-β has been shown to developmentally regulate bone mass and bone matrix properties. However, the mechanisms that control postnatal skeletal int...
Autores principales: | Mohammad, Khalid S., Chen, Carol G., Balooch, Guive, Stebbins, Elizabeth, McKenna, C. Ryan, Davis, Holly, Niewolna, Maria, Peng, Xiang Hong, Nguyen, Daniel H. N., Ionova-Martin, Sophi S., Bracey, John W., Hogue, William R., Wong, Darren H., Ritchie, Robert O., Suva, Larry J., Derynck, Rik, Guise, Theresa A., Alliston, Tamara |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666804/ https://www.ncbi.nlm.nih.gov/pubmed/19357790 http://dx.doi.org/10.1371/journal.pone.0005275 |
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