Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

BACKGROUND: Lymphatic filariasis can be associated with development of serious pathology in the form of lymphedema, hydrocele, and elephantiasis in a subset of infected patients. METHODS AND FINDINGS: To elucidate the role of CD4(+) T cell subsets in the development of lymphatic pathology, we examin...

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Detalles Bibliográficos
Autores principales: Babu, Subash, Bhat, Sajid Q., Pavan Kumar, N., Lipira, Angelo B., Kumar, Sanath, Karthik, C., Kumaraswami, V., Nutman, Thomas B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666805/
https://www.ncbi.nlm.nih.gov/pubmed/19381284
http://dx.doi.org/10.1371/journal.pntd.0000420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666805/
https://www.ncbi.nlm.nih.gov/pubmed/19381284
http://dx.doi.org/10.1371/journal.pntd.0000420

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