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The RNA Polymerase Dictates ORF1 Requirement and Timing of LINE and SINE Retrotransposition

Mobile elements comprise close to one half of the mass of the human genome. Only LINE-1 (L1), an autonomous non-Long Terminal Repeat (LTR) retrotransposon, and its non-autonomous partners—such as the retropseudogenes, SVA, and the SINE, Alu—are currently active human retroelements. Experimental evid...

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Detalles Bibliográficos
Autores principales: Kroutter, Emily N., Belancio, Victoria P., Wagstaff, Bradley J., Roy-Engel, Astrid M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666806/
https://www.ncbi.nlm.nih.gov/pubmed/19390602
http://dx.doi.org/10.1371/journal.pgen.1000458