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Perturbation of Interaction Networks for Application to Cancer Therapy

We present a computational approach for studying the effect of potential drug combinations on the protein networks associated with tumor cells. The majority of therapeutics are designed to target single proteins, yet most diseased states are characterized by a combination of many interacting genes a...

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Detalles Bibliográficos
Autores principales: Quayle, Adrian P., Siddiqui, Asim S., Jones, Steven J. M.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666951/
https://www.ncbi.nlm.nih.gov/pubmed/19390668