The Toll-Like Receptor Signaling Molecule Myd88 Contributes to Pancreatic Beta-Cell Homeostasis in Response to Injury

Commensal flora and pathogenic microbes influence the incidence of diabetes in animal models yet little is known about the mechanistic basis of these interactions. We hypothesized that Myd88, an adaptor molecule in the Toll-like-receptor (TLR) pathway, regulates pancreatic β-cell function and homeos...

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Detalles Bibliográficos
Autores principales: Bollyky, Paul L., Bice, Jeffrey B., Sweet, Ian R., Falk, Ben A., Gebe, John A., Clark, April E., Gersuk, Vivian H., Aderem, Alan, Hawn, Thomas R., Nepom, Gerald T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666970/
https://www.ncbi.nlm.nih.gov/pubmed/19357791
http://dx.doi.org/10.1371/journal.pone.0005063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666970/
https://www.ncbi.nlm.nih.gov/pubmed/19357791
http://dx.doi.org/10.1371/journal.pone.0005063

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