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Human Herpesvirus Replication and Abnormal CD8+ T Cell Activation and Low CD4+ T Cell Counts in Antiretroviral-Suppressed HIV-Infected Patients

BACKGROUND: Most HIV-infected patients receiving virologically suppressive antiretroviral therapy continue to have abnormal, generalized T cell activation. We explored whether the degree of ongoing cytomegalovirus (CMV), Epstein-Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) replicati...

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Detalles Bibliográficos
Autores principales: Jacobson, Mark A., Ditmer, Dirk P., Sinclair, Elizabeth, Martin, Jeffrey N., Deeks, Steven G., Hunt, Peter, Mocarski, Edward S., Shiboski, Caroline
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667217/
https://www.ncbi.nlm.nih.gov/pubmed/19381272
http://dx.doi.org/10.1371/journal.pone.0005277