Cargando…

Unc119 Protects from Shigella Infection by Inhibiting the Abl Family Kinases

BACKGROUND: Bacteria engage cell surface receptors and intracellular signaling molecules to enter the cell. Unc119 is an adaptor protein, which interacts with receptors and tyrosine kinases. Its role in bacterial invasion of cells is unknown. METHODOLOGY/PRINCIPAL FINDINGS: We used biochemical, mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Vepachedu, Ramarao, Karim, Zunayet, Patel, Ojas, Goplen, Nicholas, Alam, Rafeul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667249/
https://www.ncbi.nlm.nih.gov/pubmed/19381274
http://dx.doi.org/10.1371/journal.pone.0005211