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Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling

BACKGROUND: During normal physical activities cartilage experiences dynamic compressive forces that are essential to maintain cartilage integrity. However, at non-physiologic levels these signals can induce inflammation and initiate cartilage destruction. Here, by examining the pro-inflammatory sign...

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Detalles Bibliográficos
Autores principales: Nam, Jin, Aguda, Baltazar D., Rath, Bjoern, Agarwal, Sudha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667254/
https://www.ncbi.nlm.nih.gov/pubmed/19370157
http://dx.doi.org/10.1371/journal.pone.0005262