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Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling
BACKGROUND: During normal physical activities cartilage experiences dynamic compressive forces that are essential to maintain cartilage integrity. However, at non-physiologic levels these signals can induce inflammation and initiate cartilage destruction. Here, by examining the pro-inflammatory sign...
Autores principales: | Nam, Jin, Aguda, Baltazar D., Rath, Bjoern, Agarwal, Sudha |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667254/ https://www.ncbi.nlm.nih.gov/pubmed/19370157 http://dx.doi.org/10.1371/journal.pone.0005262 |
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