Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways

BACKGROUND: Calorie restriction (CR) is the only intervention known to extend lifespan in a wide range of organisms, including mammals. However, the mechanisms by which it regulates mammalian aging remain largely unknown, and the involvement of the TOR and sirtuin pathways (which regulate aging in s...

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Detalles Bibliográficos
Autores principales: Estep, Preston Wayne, Warner, Jason B., Bulyk, Martha L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667255/
https://www.ncbi.nlm.nih.gov/pubmed/19370158
http://dx.doi.org/10.1371/journal.pone.0005242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667255/
https://www.ncbi.nlm.nih.gov/pubmed/19370158
http://dx.doi.org/10.1371/journal.pone.0005242

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