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Phasevarions Mediate Random Switching of Gene Expression in Pathogenic Neisseria

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, the random switching of the modA gene controls expression of a phase-variable reg...

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Detalles Bibliográficos
Autores principales: Srikhanta, Yogitha N., Dowideit, Stefanie J., Edwards, Jennifer L., Falsetta, Megan L., Wu, Hsing-Ju, Harrison, Odile B., Fox, Kate L., Seib, Kate L., Maguire, Tina L., Wang, Andrew H.-J., Maiden, Martin C., Grimmond, Sean M., Apicella, Michael A., Jennings, Michael P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667262/
https://www.ncbi.nlm.nih.gov/pubmed/19390608
http://dx.doi.org/10.1371/journal.ppat.1000400