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Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz
Metabolic homeostasis in metazoans is regulated by endocrine control of insulin/IGF signaling (IIS) activity. Stress and inflammatory signaling pathways—such as Jun-N-terminal Kinase (JNK) signaling—repress IIS, curtailing anabolic processes to promote stress tolerance and extend lifespan. While thi...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667264/ https://www.ncbi.nlm.nih.gov/pubmed/19390610 http://dx.doi.org/10.1371/journal.pgen.1000460 |