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Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz

Metabolic homeostasis in metazoans is regulated by endocrine control of insulin/IGF signaling (IIS) activity. Stress and inflammatory signaling pathways—such as Jun-N-terminal Kinase (JNK) signaling—repress IIS, curtailing anabolic processes to promote stress tolerance and extend lifespan. While thi...

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Detalles Bibliográficos
Autores principales: Hull-Thompson, Julie, Muffat, Julien, Sanchez, Diego, Walker, David W., Benzer, Seymour, Ganfornina, Maria D., Jasper, Heinrich
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667264/
https://www.ncbi.nlm.nih.gov/pubmed/19390610
http://dx.doi.org/10.1371/journal.pgen.1000460