The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1

An extensive protein–protein interaction network has been identified between proteins implicated in inherited ataxias. The protein sacsin, which is mutated in the early-onset neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay, is a node in this interactome. Here, we...

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Detalles Bibliográficos
Autores principales: Parfitt, David A., Michael, Gregory J., Vermeulen, Esmeralda G.M., Prodromou, Natalia V., Webb, Tom R., Gallo, Jean-Marc, Cheetham, Michael E., Nicoll, William S., Blatch, Gregory L., Chapple, J. Paul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667285/
https://www.ncbi.nlm.nih.gov/pubmed/19208651
http://dx.doi.org/10.1093/hmg/ddp067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667285/
https://www.ncbi.nlm.nih.gov/pubmed/19208651
http://dx.doi.org/10.1093/hmg/ddp067

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