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The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1
An extensive protein–protein interaction network has been identified between proteins implicated in inherited ataxias. The protein sacsin, which is mutated in the early-onset neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix-Saguenay, is a node in this interactome. Here, we...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667285/ https://www.ncbi.nlm.nih.gov/pubmed/19208651 http://dx.doi.org/10.1093/hmg/ddp067 |