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Chronic Pharmacological and Safety Evaluation of Hematide™, a PEGylated Peptidic Erythropoiesis-Stimulating Agent, in Rodents

Hematide™ is a synthetic peptide-based, PEGylated erythropoiesis-stimulating agent, which is being developed for the chronic treatment of anaemia associated with chronic renal failure. To support the safety of long-term dosing of chronic renal failure patients, a comprehensive toxicology programme w...

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Detalles Bibliográficos
Autores principales: Woodburn, Kathryn W, Wilson, Susan D, Fong, Kei-Lai, Schatz, Peter J, Spainhour, Charles B, Norton, Daniel
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667308/
https://www.ncbi.nlm.nih.gov/pubmed/19143750
http://dx.doi.org/10.1111/j.1742-7843.2008.00347.x