Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production

BACKGROUND: There is evidence from previous works that bacterial secondary metabolism may be stimulated by genetic manipulation of RNA polymerase (RNAP). In this study we have used rifampicin selection as a strategy to genetically improve the erythromycin producer Saccharopolyspora erythraea. RESULT...

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Detalles Bibliográficos
Autores principales: Carata, Elisabetta, Peano, Clelia, Tredici, Salvatore M, Ferrari, Francesco, Talà, Adelfia, Corti, Giorgio, Bicciato, Silvio, De Bellis, Gianluca, Alifano, Pietro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667423/
https://www.ncbi.nlm.nih.gov/pubmed/19331655
http://dx.doi.org/10.1186/1475-2859-8-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667423/
https://www.ncbi.nlm.nih.gov/pubmed/19331655
http://dx.doi.org/10.1186/1475-2859-8-18

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