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An automatic method for assessing structural importance of amino acid positions

BACKGROUND: A great deal is known about the qualitative aspects of the sequence-structure relationship, for example that buried residues are usually more conserved between structurally similar homologues, but no attempts have been made to quantitate the relationship between evolutionary conservation...

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Detalles Bibliográficos
Autores principales: Sadowski, Michael I, Jones, David T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667441/
https://www.ncbi.nlm.nih.gov/pubmed/19261183
http://dx.doi.org/10.1186/1472-6807-9-10