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Decomposing complex reaction networks using random sampling, principal component analysis and basis rotation

BACKGROUND: Metabolism and its regulation constitute a large fraction of the molecular activity within cells. The control of cellular metabolic state is mediated by numerous molecular mechanisms, which in effect position the metabolic network flux state at specific locations within a mathematically-...

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Detalles Bibliográficos
Autores principales: Barrett, Christian L, Herrgard, Markus J, Palsson, Bernhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667477/
https://www.ncbi.nlm.nih.gov/pubmed/19267928
http://dx.doi.org/10.1186/1752-0509-3-30