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CDK4 IVS4-nt40 AA genotype and obesity-associated tumors/cancer in Italians – a case-control study
BACKGROUND: Cell cycle checkpoint regulation is crucial for prevention of tumor in mammalian cells. Cyclin-dependant kinase 4 (CDK4) is important in cell cycle regulation, as it controls the G1-S phase of the cell cycle. CDK4 has potential mitogenic properties through phosphorylation of target prote...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667486/ https://www.ncbi.nlm.nih.gov/pubmed/19327170 http://dx.doi.org/10.1186/1756-9966-28-42 |