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CDK4 IVS4-nt40 AA genotype and obesity-associated tumors/cancer in Italians – a case-control study

BACKGROUND: Cell cycle checkpoint regulation is crucial for prevention of tumor in mammalian cells. Cyclin-dependant kinase 4 (CDK4) is important in cell cycle regulation, as it controls the G1-S phase of the cell cycle. CDK4 has potential mitogenic properties through phosphorylation of target prote...

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Detalles Bibliográficos
Autores principales: Meenakshisundaram, Ramachandran, Gragnoli, Claudia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667486/
https://www.ncbi.nlm.nih.gov/pubmed/19327170
http://dx.doi.org/10.1186/1756-9966-28-42