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Dynamic distribution and expression in vivo of the human interferon gamma gene delivered by adenoviral vector

BACKGROUND: We previously found that r-hu-IFNγ exerts a potent anti-tumor effect on human nasopharyngeal carcinoma xenografts in vivo. Considering the fact that the clinical use of recombinant IFNγ is limited by its short half-life and systemic side effects, we developed a recombinant adenovirus, Ad...

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Detalles Bibliográficos
Autores principales: Wu, Jiangxue, Xiao, Xia, Jia, Hongyun, Chen, Jiemin, Zhu, Yinghui, Zhao, Peng, Lin, Huanxin, Huang, Wenlin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667533/
https://www.ncbi.nlm.nih.gov/pubmed/19216804
http://dx.doi.org/10.1186/1471-2407-9-55