Effects of the single nucleotide polymorphism at MDM2 309 on breast cancer patients with/without BRCA1/2 mutations

BACKGROUND: A germ line single nucleotide polymorphism (SNP) in the first intron of the gene encoding MDM2 at position 309, an important modulator of p53, has been described. BRCA1/2 mutation have been associated with increased rates of breast cancers with mutated P53. It was shown that the presence...

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Detalles Bibliográficos
Autores principales: Nechushtan, Hovav, Hamburger, Tamar, Mendelson, Susan, Kadouri, Luna, Sharon, Nir, Pikarsky, Eli, Peretz, Tamar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667534/
https://www.ncbi.nlm.nih.gov/pubmed/19226467
http://dx.doi.org/10.1186/1471-2407-9-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667534/
https://www.ncbi.nlm.nih.gov/pubmed/19226467
http://dx.doi.org/10.1186/1471-2407-9-60

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