The Transcription Factor NFAT5 Is Required for Cyclin Expression and Cell Cycle Progression in Cells Exposed to Hypertonic Stress

BACKGROUND: Hypertonicity can perturb cellular functions, induce DNA damage-like responses and inhibit proliferation. The transcription factor NFAT5 induces osmoprotective gene products that allow cells to adapt to sustained hypertonic conditions. Although it is known that NFAT5-deficient lymphocyte...

Descripción completa

Detalles Bibliográficos
Autores principales: Drews-Elger, Katherine, Ortells, M. Carmen, Rao, Anjana, López-Rodriguez, Cristina, Aramburu, Jose
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667631/
https://www.ncbi.nlm.nih.gov/pubmed/19381288
http://dx.doi.org/10.1371/journal.pone.0005245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667631/
https://www.ncbi.nlm.nih.gov/pubmed/19381288
http://dx.doi.org/10.1371/journal.pone.0005245

Ejemplares similares