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The Transcription Factor NFAT5 Is Required for Cyclin Expression and Cell Cycle Progression in Cells Exposed to Hypertonic Stress

BACKGROUND: Hypertonicity can perturb cellular functions, induce DNA damage-like responses and inhibit proliferation. The transcription factor NFAT5 induces osmoprotective gene products that allow cells to adapt to sustained hypertonic conditions. Although it is known that NFAT5-deficient lymphocyte...

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Detalles Bibliográficos
Autores principales:	Drews-Elger, Katherine, Ortells, M. Carmen, Rao, Anjana, López-Rodriguez, Cristina, Aramburu, Jose
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667631/ https://www.ncbi.nlm.nih.gov/pubmed/19381288 http://dx.doi.org/10.1371/journal.pone.0005245

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