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Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine

Covalent modification by methylation of cytosine residues represents an important epigenetic hallmark. While sequence analysis after bisulphite conversion allows correlative analyses with single-base resolution, functional analysis by interference with DNA methylation is less precise, due to the com...

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Detalles Bibliográficos
Autores principales: Baubec, Tuncay, Pecinka, Ales, Rozhon, Wilfried, Mittelsten Scheid, Ortrun
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667684/
https://www.ncbi.nlm.nih.gov/pubmed/18826433
http://dx.doi.org/10.1111/j.1365-313X.2008.03699.x