The overexpression of major antioxidant enzymes does not extend the lifespan of mice

We evaluated the effect of overexpressing antioxidant enzymes on the lifespans of transgenic mice that overexpress copper zinc superoxide dismutase (CuZnSOD), catalase, or combinations of either CuZnSOD and catalase or CuZnSOD and manganese superoxide dismutase (MnSOD). Our results show that the ove...

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Detalles Bibliográficos
Autores principales: Pérez, Viviana I, Van Remmen, Holly, Bokov, Alex, Epstein, Charles J, Vijg, Jan, Richardson, Arlan
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667893/
https://www.ncbi.nlm.nih.gov/pubmed/19077044
http://dx.doi.org/10.1111/j.1474-9726.2008.00449.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667893/
https://www.ncbi.nlm.nih.gov/pubmed/19077044
http://dx.doi.org/10.1111/j.1474-9726.2008.00449.x

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