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Potential Hepatotoxicity of Efavirenz and Saquinavir/Ritonavir Coadministration in Healthy Volunteers
OBJECTIVE: This study was designed to investigate the pharmacokinetic effects of coadministration of saquinavir/ritonavir with efavirenz at steady state. METHODS: Healthy volunteers in this open-label, two-arm, one-sequence, two-period crossover study (planned enrollment of 40 participants) were ran...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Inc
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667896/ https://www.ncbi.nlm.nih.gov/pubmed/19381337 http://dx.doi.org/10.1111/j.1753-5174.2009.00016.x |