TGF-β1-Induced Expression of the Poor Prognosis SERPINE1/PAI-1 Gene Requires EGFR Signaling: A New Target for Anti-EGFR Therapy

Increased transforming growth factor-β (TGF-β) expression and epidermal growth factor receptor (EGFR) amplification accompany the emergence of highly aggressive human carcinomas. Cooperative signaling between these two growth factor/receptor systems promotes cell migration and synthesis of stromal r...

Descripción completa

Detalles Bibliográficos
Autores principales: Samarakoon, Rohan, Higgins, Craig E., Higgins, Stephen P., Higgins, Paul J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667932/
https://www.ncbi.nlm.nih.gov/pubmed/19365582
http://dx.doi.org/10.1155/2009/342391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667932/
https://www.ncbi.nlm.nih.gov/pubmed/19365582
http://dx.doi.org/10.1155/2009/342391

Ejemplares similares