A Structural Model of the Pore-Forming Region of the Skeletal Muscle Ryanodine Receptor (RyR1)

Ryanodine receptors (RyRs) are ion channels that regulate muscle contraction by releasing calcium ions from intracellular stores into the cytoplasm. Mutations in skeletal muscle RyR (RyR1) give rise to congenital diseases such as central core disease. The absence of high-resolution structures of RyR...

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Detalles Bibliográficos
Autores principales: Ramachandran, Srinivas, Serohijos, Adrian W. R., Xu, Le, Meissner, Gerhard, Dokholyan, Nikolay V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668181/
https://www.ncbi.nlm.nih.gov/pubmed/19390614
http://dx.doi.org/10.1371/journal.pcbi.1000367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668181/
https://www.ncbi.nlm.nih.gov/pubmed/19390614
http://dx.doi.org/10.1371/journal.pcbi.1000367

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