Global mapping of protein-DNA interactions in vivo by digital genomic footprinting

The orchestrated binding of transcriptional activators and repressors to specific DNA sequences in the context of chromatin defines the regulatory program of eukaryotic genomes. We developed a digital approach to assay regulatory protein occupancy on genomic DNA in vivo by dense mapping of individua...

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Detalles Bibliográficos
Autores principales: Hesselberth, Jay R., Chen, Xiaoyu, Zhang, Zhihong, Sabo, Peter J., Sandstrom, Richard, Reynolds, Alex P., Thurman, Robert E., Neph, Shane, Kuehn, Michael S., Noble, William S., Fields, Stanley, Stamatoyannopoulos, John A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668528/
https://www.ncbi.nlm.nih.gov/pubmed/19305407
http://dx.doi.org/10.1038/nmeth.1313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668528/
https://www.ncbi.nlm.nih.gov/pubmed/19305407
http://dx.doi.org/10.1038/nmeth.1313

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