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Accurate Prediction of Secreted Substrates and Identification of a Conserved Putative Secretion Signal for Type III Secretion Systems

The type III secretion system is an essential component for virulence in many Gram-negative bacteria. Though components of the secretion system apparatus are conserved, its substrates—effector proteins—are not. We have used a novel computational approach to confidently identify new secreted effector...

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Detalles Bibliográficos
Autores principales: Samudrala, Ram, Heffron, Fred, McDermott, Jason E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668754/
https://www.ncbi.nlm.nih.gov/pubmed/19390620
http://dx.doi.org/10.1371/journal.ppat.1000375