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Synaptic Vesicle Docking: Sphingosine Regulates Syntaxin1 Interaction with Munc18

Consensus exists that lipids must play key functions in synaptic activity but precise mechanistic information is limited. Acid sphingomyelinase knockout mice (ASMko) are a suitable model to address the role of sphingolipids in synaptic regulation as they recapitulate a mental retardation syndrome, N...

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Detalles Bibliográficos
Autores principales: Camoletto, Paola G., Vara, Hugo, Morando, Laura, Connell, Emma, Marletto, Fabio P., Giustetto, Maurizio, Sassoè-Pognetto, Marco, Van Veldhoven, Paul P., Ledesma, Maria Dolores
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668795/
https://www.ncbi.nlm.nih.gov/pubmed/19390577
http://dx.doi.org/10.1371/journal.pone.0005310