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Genetic correlates of autoreactivity and autoreactive potential in human Ig heavy chains
BACKGROUND: Immature bone marrow B cells are known to have longer CDR3 than mature peripheral B cells, and this genetic characteristic has been shown to correlate with autoreactivity in these early cells. B-cell Central tolerance eliminates these cells, but it is known that autoreactive B cells neve...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669064/ https://www.ncbi.nlm.nih.gov/pubmed/19250530 http://dx.doi.org/10.1186/1745-7580-5-1 |