Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms

BACKGROUND: The fidelity of DNA replication serves as the nidus for both genetic evolution and genomic instability fostering disease. Single nucleotide polymorphisms (SNPs) constitute greater than 80% of the genetic variation between individuals. A new theory regarding DNA replication fidelity has e...

Descripción completa

Detalles Bibliográficos
Autores principales: Arehart, Eric, Gleim, Scott, White, Bill, Hwa, John, Moore, Jason H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669078/
https://www.ncbi.nlm.nih.gov/pubmed/19331672
http://dx.doi.org/10.1186/1756-0381-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669078/
https://www.ncbi.nlm.nih.gov/pubmed/19331672
http://dx.doi.org/10.1186/1756-0381-2-2

Ejemplares similares