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Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae

BACKGROUND: Iron-deficiency anemia is the most prevalent form of anemia world-wide. The yeast Saccharomyces cerevisiae has been used as a model of cellular iron deficiency, in part because many of its cellular pathways are conserved. To better understand how cells respond to changes in iron availabi...

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Detalles Bibliográficos
Autores principales: Jo, William J, Kim, Jeung Hyoun, Oh, Eric, Jaramillo, Daniel, Holman, Patricia, Loguinov, Alex V, Arkin, Adam P, Nislow, Corey, Giaever, Guri, Vulpe, Chris D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669097/
https://www.ncbi.nlm.nih.gov/pubmed/19321002
http://dx.doi.org/10.1186/1471-2164-10-130