Cargando…

Short-Term Striatal Gene Expression Responses to Brain-Derived Neurotrophic Factor Are Dependent on MEK and ERK Activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is believed to be an important regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of BDNF delivery to the striatum has been implicated in the pathophysiology of Huntington's disease. Nevertheless, many...

Descripción completa

Detalles Bibliográficos
Autores principales: Gokce, Ozgun, Runne, Heike, Kuhn, Alexandre, Luthi-Carter, Ruth
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669182/
https://www.ncbi.nlm.nih.gov/pubmed/19390590
http://dx.doi.org/10.1371/journal.pone.0005292