The sigma receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

Sigma receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of ethanol. The present study tested the hypothesis that SigRs modulate ethanol reinforcement and contribute to excessive ethanol intake. The effects...

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Detalles Bibliográficos
Autores principales: Sabino, Valentina, Cottone, Pietro, Zhao, Yu, Iyer, Malliga R., Steardo, Luca, Rice, Kenner C., Conti, Bruno, Koob, George F., Zorrilla, Eric P.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669694/
https://www.ncbi.nlm.nih.gov/pubmed/18946467
http://dx.doi.org/10.1038/npp.2008.192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669694/
https://www.ncbi.nlm.nih.gov/pubmed/18946467
http://dx.doi.org/10.1038/npp.2008.192

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