Predictive diagnosis of the cancer prone Li–Fraumeni syndrome by accident: new challenges through whole genome array testing

BACKGROUND: Li–Fraumeni syndrome greatly increases the risk of developing several types of cancer and is usually caused by TP53 germline mutations. Predictive testing of at-risk family members is only offered after a complex genetic counselling process. Recently the clinical implementation of array...

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Detalles Bibliográficos
Autores principales: Schwarzbraun, T, Obenauf, A C, Langmann, A, Gruber-Sedlmayr, U, Wagner, K, Speicher, M R, Kroisel, P M
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2009
Materias:
Letters to JMG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669880/
https://www.ncbi.nlm.nih.gov/pubmed/19269943
http://dx.doi.org/10.1136/jmg.2008.064972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669880/
https://www.ncbi.nlm.nih.gov/pubmed/19269943
http://dx.doi.org/10.1136/jmg.2008.064972

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