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Stable kinetochore–microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3

Ska1 and Ska2 form a complex at the kinetochore–microtubule (KT–MT) interface and are required for timely progression from metaphase to anaphase. Here, we use mass spectrometry to search for additional components of the Ska complex. We identify C13Orf3 (now termed Ska3) as a novel member of this com...

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Detalles Bibliográficos
Autores principales: Gaitanos, Thomas N, Santamaria, Anna, Jeyaprakash, A Arockia, Wang, Bin, Conti, Elena, Nigg, Erich A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669960/
https://www.ncbi.nlm.nih.gov/pubmed/19360002
http://dx.doi.org/10.1038/emboj.2009.96