Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib

The effect of folate status on breast cancer resistance protein (BCRP)-mediated drug resistance to epidermal growth factor receptor (EGFR)-targeted drugs, such as gefitinib and erlotinib, was investigated in two human colon cancer cell lines, WiDr and Caco-2, of which the latter displayed greater se...

Descripción completa

Detalles Bibliográficos
Autores principales: Lemos, C, Kathmann, I, Giovannetti, E, Calhau, C, Jansen, G, Peters, G J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669988/
https://www.ncbi.nlm.nih.gov/pubmed/19277036
http://dx.doi.org/10.1038/sj.bjc.6604980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669988/
https://www.ncbi.nlm.nih.gov/pubmed/19277036
http://dx.doi.org/10.1038/sj.bjc.6604980

Ejemplares similares