Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential

The tumour microenvironment is believed to be involved in development, growth, metastasis, and therapy resistance of many cancers. Here we show survivin, a member of the inhibitor of apoptosis protein (IAP) family, implicated in apoptosis inhibition and the regulation of mitosis in cancer cells, exi...

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Detalles Bibliográficos
Autores principales: Khan, S, Aspe, J R, Asumen, M G, Almaguel, F, Odumosu, O, Acevedo-Martinez, S, De Leon, M, Langridge, W H R, Wall, N R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669990/
https://www.ncbi.nlm.nih.gov/pubmed/19293795
http://dx.doi.org/10.1038/sj.bjc.6604978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669990/
https://www.ncbi.nlm.nih.gov/pubmed/19293795
http://dx.doi.org/10.1038/sj.bjc.6604978

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