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Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
Secreted Frizzled-related protein-1 (sFRP1) associates with Wnt proteins and its loss can lead to activation of Wnt/β-catenin signalling. It is frequently downregulated in cancer, including prostate cancer, but its function in prostate cancer is unclear because it can increase proliferation of prost...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669996/ https://www.ncbi.nlm.nih.gov/pubmed/19277043 http://dx.doi.org/10.1038/sj.bjc.6604976 |