Cargando…

Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes

Vascular endothelial growth factor (VEGF) inhibits differentiation and maturation of dendritic cells (DC), suggesting a potential immunosuppressive role for this proangiogenic factor. Bevacizumab, sorafenib and sunitinib target VEGF-mediated angiogenesis and are active against several types of cance...

Descripción completa

Detalles Bibliográficos
Autores principales: Alfaro, C, Suarez, N, Gonzalez, A, Solano, S, Erro, L, Dubrot, J, Palazon, A, Hervas-Stubbs, S, Gurpide, A, Lopez-Picazo, J M, Grande-Pulido, E, Melero, I, Perez-Gracia, J L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670006/
https://www.ncbi.nlm.nih.gov/pubmed/19277038
http://dx.doi.org/10.1038/sj.bjc.6604965