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Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

Complement is an essential component of the innate and acquired immune system1, and consists of a series of proteolytic cascades that are initiated by the presence of micro-organisms. In health, activation of complement is precisely controlled through membrane-bound and soluble plasma-regulatory pro...

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Detalles Bibliográficos
Autores principales: Schneider, Muriel C., Prosser, Beverly E., Caesar, Joseph J.E., Kugelberg, Elisabeth, Li, Su, Zhang, Qian, Quoraishi, Sadik, Lovett, Janet E., Deane, Janet E., Sim, Robert B., Roversi, Pietro, Johnson, Steven, Tang, Christoph M., Lea, Susan M.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670278/
https://www.ncbi.nlm.nih.gov/pubmed/19225461
http://dx.doi.org/10.1038/nature07769