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HIV blocking antibodies following immunisation with chimaeric peptides coding a short N-terminal sequence of the CCR5 receptor

The chemokine receptor CCR5 is required for cellular entry by many strains of HIV, and provides a potential target for molecules, including antibodies, designed to block HIV transmission. This study investigates a novel approach to stimulate antibodies to CCR5. Rabbits were immunised with chimaeric...

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Detalles Bibliográficos
Autores principales: Chain, Benjamin M., Noursadeghi, Mahdad, Gardener, Michelle, Tsang, Jhen, Wright, Edward
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670972/
https://www.ncbi.nlm.nih.gov/pubmed/18765264
http://dx.doi.org/10.1016/j.vaccine.2008.08.025