Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

Enzymatic cleavage of the glycosidic bond yields products in which the anomeric configuration is either retained or inverted. Each mechanism reflects the dispositions of the enzyme functional groups; a facet of which is essentially conserved in 113 glycoside hydrolase (GH) families. We show that fam...

Descripción completa

Detalles Bibliográficos
Autores principales: Gloster, Tracey M., Turkenburg, Johan P., Potts, Jennifer R., Henrissat, Bernard, Davies, Gideon J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670981/
https://www.ncbi.nlm.nih.gov/pubmed/18848471
http://dx.doi.org/10.1016/j.chembiol.2008.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670981/
https://www.ncbi.nlm.nih.gov/pubmed/18848471
http://dx.doi.org/10.1016/j.chembiol.2008.09.005

Ejemplares similares