Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

OBJECTIVE: Interleukin (IL)-21 is a type 1 cytokine that has been implicated in the pathogenesis of type 1 diabetes via the unique biology of the nonobese diabetic (NOD) mouse strain. The aim of this study was to investigate a causal role for IL-21 in type 1 diabetes. RESEARCH DESIGN AND METHODS: We...

Descripción completa

Detalles Bibliográficos
Autores principales: Sutherland, Andrew P.R., Van Belle, Tom, Wurster, Andrea L., Suto, Akira, Michaud, Monia, Zhang, Dorothy, Grusby, Michael J., von Herrath, Matthias
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671036/
https://www.ncbi.nlm.nih.gov/pubmed/19208913
http://dx.doi.org/10.2337/db08-0882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671036/
https://www.ncbi.nlm.nih.gov/pubmed/19208913
http://dx.doi.org/10.2337/db08-0882

Ejemplares similares